Author

K. Maisel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Immunology· 2 Cell Biology· 1 Pathology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:mouse· 4 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:batch correction / integration· 2 Research Focus:clustering· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

J. C. McCright· 3 shared J. McCright· 2 shared J. Yarmovsky· 2 shared K. Moore· 2 shared M. Amosu· 2 shared A. C. Racanelli· 1 shared A. J. Gregory· 1 shared A. M. Jankowski· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersBioengineering

J. C. McCright

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Mechanical Dissociation of Tissues for Single Cell Analysis Using a Simple Motorized Device

M. Amosu, A. J. Gregory, J. D. Murtagh, N. Pavin, C. T. Meyers, J. Grano de Oro Fernandez, K. Moore, K. Maisel

This paper introduces a low-cost motorized device for automated tissue dissociation, improving reproducibility and reducing time compared to manual methods.

bioRxiv · May 3, 2023Cell Biology

Para- and transcellular transport kinetics of nanoparticles across lymphatic endothelial cells

J. McCright, J. Yarmovsky, K. Maisel

The paper develops a computational model to quantify nanoparticle transport kinetics across lymphatic endothelial cells, identifying transcellular mechanisms as key drivers.

bioRxiv · Apr 12, 2023Bioengineering

Plasmacytoid dendritic cells mediate CpG-ODN induced increase in survival in a mouse model of lymphangioleiomyomatosis

M. Amosu, A. M. Jankowski, J. C. McCright, B. Yang, J. G. d. O. Fernandez, K. Moore, H. S. Gadde, M. Kaluzienski, K. Maisel

This study shows that CpG-ODN improves survival in a mouse LAM model by enhancing immune responses, mediated by plasmacytoid dendritic cells, and synergizes with anti-PD1 and rapamycin.

bioRxiv · Feb 6, 2023Immunology

Multiple particle tracking (MPT) using PEGylated nanoparticles reveals heterogeneity within murine lymph nodes and between lymph nodes at different locations

A. Ramirez, B. Merwitz, H. Lee, E. Vaughan, K. Maisel

The paper uses PEGylated nanoparticles and multiple particle tracking to study lymph node interstitial properties, finding pore sizes smaller than previously thought and location-dependent diffusion.

bioRxiv · Jun 2, 2022Immunology

Discussion-based DEI education to help create inclusive and open BME research lab environments

R. Naiknavare, K. Maisel

The paper describes a DEI education initiative using group discussions to foster inclusivity in biomedical engineering labs, reporting improved belonging and awareness among trainees.

bioRxiv · Mar 30, 2022Scientific Communication & Education

Generating an in vitro gut model with physiologically relevant biophysical mucus properties

J. C. McCright, A. Sinha, K. Maisel

This study creates an in vitro gut model with mucus properties similar to porcine tissue, using Caco-2 and HT29-MTX cells, and shows how cell ratios affect mucus biophysical characteristics.

bioRxiv · Feb 18, 2022Bioengineering

Lymphatic Thrombosis and Impaired Lymph Drainage in Cigarette Smoke-Associated Emphysema

B. D. Summers, K. Kim, Z. Khan, S. Thangaswamy, C. C. Clement, J. McCright, K. Maisel, S. Zamora, S. Quintero, A. C. Racanelli, J. Yang, J. D'Armiento, L. A. Monticelli, M. L. Kahn, A. M. K. Choi, , H. O. Reed

This study shows cigarette smoke causes lung lymphatic thrombosis and dysfunction in mice and humans, linking it to emphysema pathogenesis.

bioRxiv · Nov 23, 2021 · PreprintPathology

Dense poly(ethylene glycol) coatings maximize nanoparticle transport across lymphatic endothelial cells and accumulate in the skin draining lymph nodes

J. C. McCright, C. Skeen, J. Yarmovsky, K. Maisel

This study shows dense PEG coatings on nanoparticles enhance transport across lymphatic endothelial cells and accumulation in draining lymph nodes, with optimal PEG density and conformation.

bioRxiv · Aug 1, 2020Bioengineering