Author

Z. Khan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Cancer Biology· 1 Pathology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:drug response / drug discovery· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Assay:metabolomics· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:whole-genome sequencing· 2

Frequent Co-Authors

H. van Bakel· 2 shared A. Bashir· 1 shared A. C. Racanelli· 1 shared A. Coates· 1 shared A. H. Y. Chan· 1 shared A. Kam· 1 shared A. Kasarskis· 1 shared A. M. Allen· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

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2 shared papersMicrobiology

H. van Bakel

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

ALDH1A3-acetaldehyde metabolism potentiates transcriptionalheterogeneity in melanoma

Y. Lu, J. Travnickova, M. Badonyi, F. Rambow, A. Coates, Z. Khan, J. Marques, L. Murphy, P. Garcia-Martinez, R. Marais, P. Louphrasitthiphol, A. H. Y. Chan, C. J. Schofield, A. V. Kriegsheim, J. A. Marsh, , E. E. Patton

This study shows ALDH1A3 and ACSS2 coordinate acetaldehyde-acetyl-CoA metabolism with histone acetylation in melanoma, contributing to transcriptional heterogeneity and drug resistance.

bioRxiv · Oct 28, 2023Cancer Biology

Genomic, transcriptomic, and metabolomic analysis of Traditional Chinese Medicine plant Oldenlandia corymbosa reveals the biosynthesis and mode of action of anti-cancer metabolites

I. Julca, D. Mutwil-Anderwald, V. Manoj, Z. Khan, S. K. Lai, L. K. Yang, I. T. Beh, J. Dziekan, Y. P. Lim, S. K. Lim, Y. W. Low, Y. I. Lam, Y. Mu, Q. W. Tan, P. Nuc, , M. Mutwil

This study identifies ursolic acid as the main anti-cancer compound in Oldenlandia corymbosa and reveals its mode of action through genomic, transcriptomic, and metabolomic analysis.

bioRxiv · Jun 14, 2022 · PreprintPlant Biology

Lymphatic Thrombosis and Impaired Lymph Drainage in Cigarette Smoke-Associated Emphysema

B. D. Summers, K. Kim, Z. Khan, S. Thangaswamy, C. C. Clement, J. McCright, K. Maisel, S. Zamora, S. Quintero, A. C. Racanelli, J. Yang, J. D'Armiento, L. A. Monticelli, M. L. Kahn, A. M. K. Choi, , H. O. Reed

This study shows cigarette smoke causes lung lymphatic thrombosis and dysfunction in mice and humans, linking it to emphysema pathogenesis.

bioRxiv · Nov 23, 2021 · PreprintPathology

Respiratory tract explant infection dynamics of influenza A virus in California sea lions, northern elephant seals, and rhesus macaques

H. Liu, M. Plancarte, E. E. Ball, C. M. Weiss, O. Gonzales-Viera, K. Holcomb, Z.-M. Ma, A. M. Allen, J. R. Reader, P. J. Duignan, B. Halaska, Z. Khan, D. Kriti, J. Dutta, H. van Bakel, , L. L. Coffey

This study uses respiratory tract explants from marine mammals and rhesus macaques to compare influenza A virus infection kinetics across species.

bioRxiv · Oct 15, 2020Microbiology

Combinatorial Library Designing and Virtual Screening of Cryptolepine Derivatives against Topoisomerase IIA by Molecular Docking

Maria, Z. Khan

This paper designs a combinatorial library of cryptolepine derivatives and virtually screens them against TOP2A using molecular docking to identify compounds with higher binding affinity than cryptolepine itself.

bioRxiv · Jun 8, 2020Biochemistry

Complete genome screening of clinical MRSA isolates identifies lineage diversity and provides full resolution of transmission and outbreak events

M. J. Sullivan, D. R. Altman, K. I. Chacko, B. Ciferri, E. Webster, T. R. Pak, G. Deikus, M. Lewis-Sandari, Z. Khan, C. Beckford, A. Rendo, F. Samaroo, R. Sebra, R. Karam-Howlin, T. Dingle, , H. van Bakel

This study uses long-read sequencing to analyze MRSA genomes, revealing lineage diversity and detailed transmission dynamics in an outbreak.

bioRxiv · May 21, 2019 · PreprintMicrobiology