Glioblastoma cells imitate neuronal excitability in humans
T. Tong, J. D. Hendriksen, K. J. Elbaek, A. Ozsvar, J. T. Eschen, F. G. Rodriguez-Gonzalez, I. D. Pusat, E. L. Christensen, M. Rahbaek, K. P. Frederiksen, S. O. S. Cortnum, A. K. Sindby, K. Meier, N. Mikic, J. C. H. Sorensen, , A. R. Korshoj
This study identifies that glioblastoma cells in the tumor's invasive leading edge exhibit electrophysiological properties similar to neurons, including action potentials, and show reduced proliferation signaling.
bioRxiv · Jan 8, 2024 · PreprintCancer Biology