T. Tong

Impact of Glycan Depletion, Glycan Debranching and Increased Glycan Charge on HIV-1 Neutralization Sensitivity and Immunogenicity

This study evaluates glycoengineered HIV-1 trimers to enhance bNAb recognition, finding that B4GalT1+ST6GalT1 modifications increase antibody titers in infected donors but reduce vaccine-induced neutralizing antibodies.

Efficient Gene Editing and Overexpression of Gametophyte Transformation in a Model Fern

This paper develops a CRISPR/Cas9 system for efficient gene editing and overexpression in the fern Ceratopteris richardii, demonstrating functional effects on stomatal and photosynthetic traits.

Glioblastoma cells imitate neuronal excitability in humans

This study identifies that glioblastoma cells in the tumor's invasive leading edge exhibit electrophysiological properties similar to neurons, including action potentials, and show reduced proliferation signaling.

USP10 strikes down β-catenin by dual-wielding deubiquitinase activity and phase transition potential

This study identifies USP10 as a novel regulator of β-catenin through dual mechanisms involving deubiquitination and phase separation, with implications for cancer treatment.

Impact of Common Modifications on the Antigenic Profile and Glycosylation of Membrane-Expressed HIV-1 Envelope Glycoprotein.

This study evaluates how stabilizing mutations in HIV-1 Env affect trimer stability, antigenicity, and glycosylation when expressed on membrane-expressed VLPs, finding some mutations reduce neutralizing antibody binding and alter glycan processing.

Molecular Evolution and Interaction of 14-3-3 Proteins with H+-ATPases in Plant Abiotic Stresses

This paper reviews the roles of 14-3-3 proteins and H+-ATPases in plant abiotic stress responses and analyzes their molecular evolution across species.

Protein kinase D1 phosphorylates CBX8 to facilitate the disassociation of PRC1 complex from p16 promoter and promotes cell senescence

This study shows PKD1 phosphorylates CBX8, disrupting PRC1 complex binding and promoting cell senescence by derepressing p16.

Identifying the Biosynthetic Gene Cluster for Triacsins with an N-hydroxytriazene Moiety

This study identifies the biosynthetic gene cluster for triacsins in Streptomyces aureofaciens and discovers a new producer species.