BioengineeringbioRxivPreprint
Frame Editors for Precise, Template-Free Frameshifting
S. Nakade, K. Nakamae, T.-C. Tang…·T. K. Lu
This paper introduces Frame Editors (FEs) that improve CRISPR-Cas9 editing accuracy by inducing controlled frameshifts without templates, reducing random mutations and off-target effects.
DOI 10.1101/2022.12.05.518807