Author

K. Neupane

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Biophysics· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

M. T. Woodside· 3 shared S. M. Ileperuma· 3 shared S. Munshi· 3 shared D. B. Ritchie· 2 shared E. Opoku· 2 shared J. Smith· 2 shared K. Gulshan· 2 shared M. Zhao· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

M. T. Woodside

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Disulfiram reduces atherosclerosis and enhances efferocytosis, autophagy, and atheroprotective gut microbiota in hyperlipidemic mice.

C. A. Traughber, K. Timinski, A. Prince, N. Bhandari, K. Neupane, M. R. Khan, E. Opoku, E. Opoku, G. Brubaker, K. Nageshwar, E. G. Ertugral, P. Naggareddy, C. R. Kothapalli, J. Smith, K. Gulshan

bioRxiv · Oct 17, 2023Cell Biology

Myeloid-cell-specific role of Gasdermin D in promoting lung cancer progression in mice.

c. Traughber, G. deshpande, k. neupane, M. Khan, M. R. McMullen, S. Swaidani, E. Opoku, S. Muppals, J. Smith, L. Nagy, K. Gulshan

This study shows that GsdmD in myeloid cells promotes lung cancer metastasis in mice by enhancing inflammasome activity and IL-1β release.

bioRxiv · Aug 22, 2022Cancer Biology

Small-molecule ligands can inhibit -1 programmed ribosomal frameshifting in a broad spectrum of coronaviruses

S. Munshi, K. Neupane, S. M. Ileperuma, M. T. Halma, J. A. Kelly, C. F. Halpern, J. D. Dinman, S. Loerch, M. T. Woodside

The paper tests small-molecule ligands against -1 PRF in coronaviruses, finding nafamostat inhibits frameshifting in multiple bat CoVs and SARS-CoV-2 but not other viruses.

bioRxiv · Aug 6, 2021 · PreprintBiochemistry

Structural dynamics of the SARS-CoV-2 frameshift-stimulatory pseudoknot reveal topologically distinct conformers

K. Neupane, M. Zhao, A. Lyons, S. Munshi, S. M. Ileperuma, D. B. Ritchie, N. Q. Hoffer, A. Narayan, M. T. Woodside

The paper investigates the structural dynamics of the SARS-CoV-2 frameshift-stimulatory pseudoknot under tension, revealing multiple conformers and their folding mechanisms.

bioRxiv · Dec 28, 2020Biophysics

Anti-frameshifting ligand active against SARS coronavirus-2 is resistant to natural mutations of the frameshift-stimulatory pseudoknot

K. Neupane, S. Munshi, M. Zhao, D. B. Ritchie, S. M. Ileperuma, M. T. Woodside

The paper examines how natural mutations in the SARS-CoV-2 pseudoknot affect −1 PRF efficiency and the activity of anti-frameshifting ligands, finding that ligand activity remains resistant to most mutations.

bioRxiv · Jun 29, 2020Biochemistry