Author

S. M. Ileperuma

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:host-pathogen & immune response· 3 Approach:experimental assay· 2 Organism:human· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

K. Neupane· 3 shared M. T. Woodside· 3 shared S. Munshi· 3 shared D. B. Ritchie· 2 shared M. Zhao· 2 shared A. Lyons· 1 shared A. Narayan· 1 shared C. F. Halpern· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

K. Neupane

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BiochemistrybioRxivPreprintAug 6, 2021

Small-molecule ligands can inhibit -1 programmed ribosomal frameshifting in a broad spectrum of coronaviruses

S. Munshi, K. Neupane, S. M. Ileperuma…·M. T. Woodside

The paper tests small-molecule ligands against -1 PRF in coronaviruses, finding nafamostat inhibits frameshifting in multiple bat CoVs and SARS-CoV-2 but not other viruses.

DOI 10.1101/2021.08.06.455424

humanmouse

𝕏 PostBluesky

BiophysicsbioRxivDec 28, 2020

Structural dynamics of the SARS-CoV-2 frameshift-stimulatory pseudoknot reveal topologically distinct conformers

K. Neupane, M. Zhao, A. Lyons…·M. T. Woodside

The paper investigates the structural dynamics of the SARS-CoV-2 frameshift-stimulatory pseudoknot under tension, revealing multiple conformers and their folding mechanisms.

DOI 10.1038/s41467-021-25085-6

virusexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivJun 29, 2020

Anti-frameshifting ligand active against SARS coronavirus-2 is resistant to natural mutations of the frameshift-stimulatory pseudoknot

K. Neupane, S. Munshi, M. Zhao…·M. T. Woodside

The paper examines how natural mutations in the SARS-CoV-2 pseudoknot affect −1 PRF efficiency and the activity of anti-frameshifting ligands, finding that ligand activity remains resistant to most mutations.

DOI 10.1016/j.jmb.2020.09.006

humanstatistical model

𝕏 PostBluesky