MicrobiologybioRxiv
SARS-CoV-2 ORF8 is a viral cytokine regulating immune responses
M. Kohyama, T. Suzuki, W. Nakai…·H. Arase
This study shows that SARS-CoV-2 ORF8 protein acts as a cytokine that promotes lung inflammation and immune dysregulation in COVID-19, suggesting it as a potential therapeutic target.
DOI 10.1093/intimm/dxac044