Phenylpropionc acid produced by gut microbiota alleviates acetaminophen-induced hepatotoxicity
S. Cho, K.-J. Won, X. Yang, V. Leone, E. B. Chang, E. Chung, J.-S. Park, G. Guzman, H. Lee, H. Jeong
This study shows that phenylpropionic acid from gut microbiota reduces acetaminophen-induced liver damage in mice by inhibiting the toxic enzyme CYP2E1.
bioRxiv · Jun 10, 2020 · PreprintPharmacology & Toxicology