H. Jeong

The paper identifies a hidden oxidative damage pathway in proteins through O2 confinement and photoexcitation, bypassing antioxidant defenses.

The paper presents the cryo-EM structure of the C. elegans TMC-2 complex and compares it to the TMC-1 complex to identify structural features involved in mechanosensory transduction.

This study shows that choroidal macrophage polarization direction affects myopia development in mice, with M1 macrophages promoting and M2 macrophages suppressing myopia.

The paper shows that fingering patterns in epithelial layers influence gap closure speed through curvature-mediated forces, with fingering frequency inversely related to boundary curvature.

This paper introduces a self-healing PDMS material with safety-enhancing properties for wireless, skin-interfaced bioelectronic devices.

This paper introduces RI-TFM, a high-speed label-free technique for 3D cellular mechanics, and demonstrates its ability to measure traction forces and morphology in cells.

The paper determines the structure of the C. elegans TMC-1 complex using cryo-EM, revealing its composition and mechanism of mechanosensory transduction.

The paper studies the evolution of a supergene in white-throated sparrows, finding reduced recombination, low degeneration, and balancing selection maintaining genetic diversity.

This study produces recombinant monomeric human IL-22 and shows it reduces DSS-induced colitis and pro-inflammatory cytokines in mice.

This study investigates mCRP deposition in AAA and identifies associated proteomic changes and enriched pathways.

This study tests the efficacy of double-stranded RNA targeting VP1 to control and prevent sacbrood virus in Apis cerana apiaries, showing increased survival rates and safe mitigation of the virus.

This study shows that AMPK-dependent phosphorylation of TFEB/TFE3 enhances their transcriptional activity under nutrient starvation and promotes chemoresistance in cancer.

This study encodes multiple virtual signals in DNA barcodes using single-molecule FRET, enabling the differentiation of six barcodes without sequence exchange.

This study shows that FLCN gene ablation reduces fibrosis and inflammation in a diet-induced NASH model by enhancing autophagy and lysosomal biogenesis.

The paper identifies upregulated TLR4-mediated inflammatory signaling in COVID-19 patients, linking it to pathological inflammation and suggesting TLR4 as a therapeutic target.

This study shows that phenylpropionic acid from gut microbiota reduces acetaminophen-induced liver damage in mice by inhibiting the toxic enzyme CYP2E1.

This study uses molecular dynamics simulations to investigate how the R518W mutation in NPC1 affects its structure and cholesterol transport function, revealing a structural shift in the NTD that may impair NPC2 interaction.

This study shows that motor neurons enhance muscle stem cell function by boosting protein synthesis and mitochondrial activity, which is critical for muscle regeneration and is disrupted in diseases like muscular dystrophy and aging.

This paper introduces a cell-only bioink and supporting medium for 3D printing and long-term culture of functional tissues without a biomaterial scaffold.

This study identifies gut bacteria, particularly Clostridiales, as a source of tacrolimus metabolism, producing less potent metabolites that may explain variable drug exposure after oral dosing.

This study shows a soluble protein can act as a chaperone in vivo, preventing protein aggregation and aiding folding, similar to known chaperones.