Author

L. A. Borthwick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Approach:comparative / phylogenetic analysis· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. J. Fisher· 3 shared N. C. Henderson· 2 shared A. Andreasson· 1 shared A. Chhatwal· 1 shared A. M. S. Barron· 1 shared A. Nazgiewicz· 1 shared A. S. Loudon· 1 shared A. White· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersImmunology

A. J. Fisher

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivPreprintJul 1, 2022

Identification of a Broadly Fibrogenic Macrophage Subset Induced by Type 3 Inflammation in Human and Murine Liver and Lung Fibrosis

T. Fabre, A. M. S. Barron, S. M. Christensen…·K. Dower

The paper identifies a fibrogenic macrophage subset linked to liver and lung fibrosis across species and shows that targeting specific cytokines reduces fibrosis in models.

DOI 10.1101/2022.07.01.498017

humanmouse

𝕏 PostBluesky

Cell BiologybioRxivSep 25, 2019

The circadian clock protein REVERBα inhibits pulmonary fibrosis development

P. S. Cunningham, P. Meijer, A. Nazgiewicz…·J. Blaikley

This study identifies REVERBα as a regulator of pulmonary fibrosis by modulating circadian rhythms and integrin β1 focal adhesion formation in fibroblasts, with potential therapeutic implications.

DOI 10.1073/pnas.1912109117

humanbulk RNA-seq

𝕏 PostBluesky

PhysiologybioRxivPreprintApr 17, 2019

Transcriptional analysis identifies novel biomarkers associated with successful ex-vivo perfusion of human donor lungs

J. R. Ferdinand, M. I. Morrison, A. Andreasson…·A. J. Fisher

Transcriptional analysis of lungs during ex-vivo perfusion identifies CHIT1 and SCGB1A1 as potential biomarkers to distinguish transplantable from non-transplantable lungs.

DOI 10.1101/612374

humanbulk RNA-seq

𝕏 PostBluesky