J. R. Ferdinand

This study examines immune responses in human nasal-associated lymphoid tissue after SARS-CoV-2 infection, revealing coordinated defense mechanisms involving monocytes, macrophages, B cells, and T cells.

The paper finds that obesity is associated with reduced immune and inflammatory responses in COVID-19 patients, including lower expression of IFN and IFNγ response genes in lung and blood cells.

The paper tracks B cells exiting germinal centers and shows they recycle through the subcapsular sinus, interacting with macrophages and returning to GCs via CCL21 gradients, supporting affinity maturation to antigenic drift.

This study creates a cell atlas of the human thymus using scRNA-seq, revealing new cell populations and insights into T-cell development and TCR recombination.

The paper examines microbial and immune cell interactions in the human colon, identifying distinct immune niches and T cell profiles along the colon.

Transcriptional analysis of lungs during ex-vivo perfusion identifies CHIT1 and SCGB1A1 as potential biomarkers to distinguish transplantable from non-transplantable lungs.