Author

L. A. Dailey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Ghio· 1 shared A. N. Koppes· 1 shared B. Liu· 1 shared C. A. Dreiss· 1 shared C. Ghio· 1 shared C. Lorenz· 1 shared D. M. Schreinemachers· 1 shared G. N. Sekhar· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioengineering

A. Ghio

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2 papers

Recent·Most cited

Lactate production can function to increase human epithelial cell iron concentration

C. Ghio, J. M. Soukup, L. A. Dailey, A. Ghio, D. M. Schreinemachers, R. A. Koppes, A. N. Koppes

This study shows lactate can enhance iron import in human epithelial cells, LDH activity reflects iron availability, and blood LDH correlates with iron homeostasis indices.

bioRxiv · Nov 11, 2021Bioengineering

Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug.

L. Sanderson, M. da Silva, G. N. Sekhar, R. C. Brown, H. Burrell-Saward, M. Fidanboylu, B. Liu, L. A. Dailey, C. A. Dreiss, C. Lorenz, M. Christie, S. Persaud, V. Yardley, S. L. Croft, M. Valero, S. A. Thomas

This paper develops an intravenous pentamidine formulation using Pluronic micelles to enhance CNS exposure for stage 2 HAT treatment, finding no major neurotoxicity but limited BBB penetration enhancement.

bioRxiv · Apr 18, 2019Pharmacology & Toxicology