Author

S. Persaud

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cancer Biology· 1 Pathology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. D. Goldberg· 1 shared A. Dahake· 1 shared A. Dogan· 1 shared A. Llanso· 1 shared A. M. Rozeboom· 1 shared A. O. Olukoya· 1 shared A. Sciambi· 1 shared B. Liu· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperPathology

A. D. Goldberg

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Author profile →

5 papers

Recent·Most cited

Adherent reformed islets: a long-term primary cell-based platform for exploring mouse and human islet biology.

N. Haq, K. Toczyska, M. Wilson, M. Jacobs, Y. Lei, M. Zhao, J. Pearson, S. Persaud, T. Pullen, G. A. Bewick

This study develops a long-term primary cell-based platform called reformed islets to study mouse and human islet biology, showing they retain key physiological and functional features of native islets.

bioRxiv · Nov 22, 2023 · PreprintPhysiology

Dying of thirst: Osmoregulation by a hawkmoth pollinator in response to variability in ambient humidity and nectar availability

A. Dahake, S. Persaud, M. N. Jones, J. Goyret, G. Davidowitz, R. A. Raguso

This study examines osmoregulation in hawkmoths under varying humidity and nectar conditions, finding that osmolality levels and survival are significantly affected by environmental factors and feeding.

bioRxiv · Jun 27, 2023Physiology

Single cell genotypic and phenotypic analysis of measurable residual disease in acute myeloid leukemia

T. T. Robinson, R. L. Bowman, S. Persaud, Y. Liu, Q. Gao, J. Zhang, X. Sun, L. A. Miles, S. F. Cai, A. Sciambi, A. Llanso, F. A. Christopher, A. D. Goldberg, A. Dogan, M. Roshal, , W. Xiao

The paper develops a single-cell MRD assay that detects residual leukemic clones with high sensitivity and reveals clonal architecture in AML.

bioRxiv · Sep 20, 2022 · PreprintPathology

Riluzole suppresses growth and enhances response to endocrine therapy in ER+ breast cancer

A. O. Olukoya, H. Stires, S. Bahnassy, S. Persaud, Y. Guerra, S. Ranjit, S. Ma, M. I. Cruz, C. Benitez, A. M. Rozeboom, H. Ceuleers, D. L. Berry, B. M. Jacobsen, G. V. Raj, R. B. Riggins

This study shows Riluzole reduces growth and improves response to endocrine therapy in ER+ breast cancer models.

bioRxiv · Jul 30, 2020 · PreprintCancer Biology

Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug.

L. Sanderson, M. da Silva, G. N. Sekhar, R. C. Brown, H. Burrell-Saward, M. Fidanboylu, B. Liu, L. A. Dailey, C. A. Dreiss, C. Lorenz, M. Christie, S. Persaud, V. Yardley, S. L. Croft, M. Valero, S. A. Thomas

This paper develops an intravenous pentamidine formulation using Pluronic micelles to enhance CNS exposure for stage 2 HAT treatment, finding no major neurotoxicity but limited BBB penetration enhancement.

bioRxiv · Apr 18, 2019Pharmacology & Toxicology