Author

L. A. Haddock

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

G. L. Barry· 2 shared K. M. Braun· 2 shared T. C. Friedrich· 2 shared A. Mehle· 1 shared B. Livingston· 1 shared C. A. Higgins· 1 shared C. I. Gonzalez· 1 shared C. Lasalde· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

G. L. Barry

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Characterization of the mIF4G domains in the RNA surveillance protein Upf2

E. M. Colon, L. A. Haddock, C. Lasalde, Q. Lin, J. S. Ramirez-Lugo, C. I. Gonzalez

This study identifies specific residues in the mIF4G domains of Upf2 that are critical for NMD activity and translation termination in yeast.

bioRxiv · Dec 12, 2022 · PreprintBiochemistry

Avian H7N9 influenza viruses are evolutionarily constrained by stochastic processes during replication and transmission in mammals

K. M. Braun, L. A. Haddock, C. M. Crooks, G. L. Barry, J. Lalli, G. Neumann, T. Watanabe, M. Imai, S. Yamayoshi, M. Ito, Y. Kawaoka, T. C. Friedrich

This study shows that H7N9 avian influenza viruses face strong evolutionary constraints during mammalian transmission, making human adaptation unlikely without rare, stochastic events.

bioRxiv · Apr 12, 2022Microbiology

Influenza A virus undergoes compartmentalized replication in vivo dominated by stochastic bottlenecks

K. A. Amato, L. A. Haddock, K. M. Braun, V. Meliopoulos, B. Livingston, R. Honce, G. A. Schaack, E. Boehm, C. A. Higgins, G. L. Barry, K. Koelle, S. Schultz-Cherry, T. C. Friedrich, A. Mehle

This study tracks influenza A virus diversity in ferrets, showing compartmentalized replication and stochastic bottlenecks shaping genetic diversity within lung lobes.

bioRxiv · Sep 28, 2021Microbiology