Author

C. A. Higgins

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Mehle· 2 shared A. Kurland· 1 shared B. Bonaventure· 1 shared B. E. Nilsson-Payant· 1 shared B. Livingston· 1 shared B. R. Rosenberg· 1 shared B. R. tenOever· 1 shared C. J. Boyle· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMicrobiology

A. Mehle

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Influenza A virus undergoes compartmentalized replication in vivo dominated by stochastic bottlenecks

K. A. Amato, L. A. Haddock, K. M. Braun, V. Meliopoulos, B. Livingston, R. Honce, G. A. Schaack, E. Boehm, C. A. Higgins, G. L. Barry, K. Koelle, S. Schultz-Cherry, T. C. Friedrich, A. Mehle

This study tracks influenza A virus diversity in ferrets, showing compartmentalized replication and stochastic bottlenecks shaping genetic diversity within lung lobes.

bioRxiv · Sep 28, 2021Microbiology

SARS-CoV-2 hijacks p38β/MAPK11 to promote viral protein translation

C. A. Higgins, B. E. Nilsson-Payant, A. Kurland, C. Ye, T. M. Yaron, J. L. Johnson, B. Bonaventure, P. Adhikary, I. Golynker, B. R. Rosenberg, O. Danziger, M. Panis, L. C. Cantley, L. Martinez-Sobrido, B. R. tenOever, J. R. Johnson

This study identifies p38β as a critical host factor for SARS-CoV-2 replication and shows that inhibiting it reduces viral replication and cytokine production.

bioRxiv · Aug 20, 2021 · PreprintMicrobiology

Lateral pressure equalisation as a principle for designing support surfaces to prevent deep tissue pressure ulcers

C. J. Boyle, D. Carpanen, T. Pandelani, C. A. Higgins, M. A. Masen, S. D. Masouros

This paper demonstrates that applying lateral pressure can reduce deep tissue stress more effectively than traditional pressure redistribution methods in preventing pressure ulcers.

bioRxiv · Sep 27, 2019Bioengineering

EPS8 facilitates uncoating of influenza A virus

G. P. Larson, V. Tran, S. Yu, Y. Cai, C. A. Higgins, D. M. Smith, S. F. Baker, S. R. Radoshitzky, J. H. Kuhn, A. Mehle

This study identifies EPS8 as a host factor that facilitates influenza A virus uncoating by delaying nuclear import of ribonucleoprotein complexes.

bioRxiv · Mar 28, 2019Microbiology