MicrobiologybioRxivPreprint
Artemisinin-based hybrids produce intracellular proteasome inhibitors that overcome resistance in Plasmodium falciparum
W. Zhan, Y. J. Liu, C. Yang…·G. Lin
This study designs artezomibs, artemisinin-proteasome inhibitor hybrids, which overcome resistance in Plasmodium falciparum by targeting proteasomes, including those with mutations.
DOI 10.1101/2021.06.21.449268