Author

L. A. Luna

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:imaging· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. E. Clark· 2 shared B. W. Purse· 2 shared C. D. Sohl· 2 shared J. A. Bernatchez· 2 shared J. L. Siqueira-Neto· 2 shared M. Coste· 2 shared S. Beck· 2 shared Z. Zhu· 2 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

A. E. Clark

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

An acidic residue buried in the dimer interface of isocitrate dehydrogenase 1 (IDH1) helps regulate catalysis and pH sensitivity

L. A. Luna, Z. Lesecq, K. A. White, A. Hoang, D. A. Scott, O. Zagnitko, A. A. Bobkov, D. L. Barber, J. M. Schiffer, D. G. Isom, C. D. Sohl

This paper identifies an acidic residue in IDH1 that regulates catalysis and pH sensitivity through conformational changes.

bioRxiv · Apr 19, 2020Biochemistry

Activity of Selected Nucleoside Analogue ProTides against Zika Virus in Human Neural Stem Cells

J. A. Bernatchez, M. Coste, S. Beck, G. A. Wells, L. A. Luna, A. E. Clark, Z. Zhu, C. D. Sohl, B. W. Purse, J. L. Siqueira-Neto

This study evaluates the antiviral activity of nucleoside ProTides against Zika virus in human neural stem cells, identifying effective compounds and elucidating their mechanism of action.

bioRxiv · Jan 29, 2019Microbiology

Development and validation of a phenotypic high-content imaging assay for assessing the antiviral activity of small-molecule inhibitors targeting the Zika virus

J. A. Bernatchez, Z. Yang, M. Coste, J. Li, S. Beck, Y. Liu, A. E. Clark, Z. Zhu, L. A. Luna, C. Sohl, B. W. Purse, R. Li, J. L. Siqueira-Neto

The paper develops and validates a high-content imaging assay to assess antiviral activity of small-molecule inhibitors against Zika virus by detecting cytopathic effects.

bioRxiv · Apr 17, 2018Microbiology