Author

L. A. Moreau

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Perciaccante· 1 shared B. Hunsel· 1 shared D. Chowdhury· 1 shared D. Haas-Kogan· 1 shared H. Nguyen· 1 shared J. P. Kaplan· 1 shared J. Peng· 1 shared K. L. Jones· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Perciaccante

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1 paper

Recent·Most cited

Cancer BiologybioRxivNov 30, 2021

A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma

S. PAL, J. P. Kaplan, H. Nguyen…·D. Haas-Kogan

This paper identifies a druggable metabolic vulnerability in diffuse midline glioma through a CRISPR screen, showing that inhibition of DHODH reduces pyrimidine biosynthesis and extends survival in mouse models.

DOI 10.1016/j.ccell.2022.07.012

mouseproteomics

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