Author

T. Frisan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Organism:mouse· 1

Frequent Co-Authors

S. Gupta· 3 shared A. Mirazimi· 2 shared A. Vegvari· 2 shared B. S. Vinhas· 2 shared E. Saccon· 2 shared F. Mikaeloff· 2 shared J. E. Rodriguez· 2 shared U. Neogi· 2 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersMicrobiology

S. Gupta

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The Epstein-Barr virus ubiquitin deconjugase BPLF1 regulates the activity of Topoisomerase II during virus replication

J. Li, N. Nagy, J. Liu, S. Gupta, T. Frisan, T. Hennig, D. P. Cameron, L. Baranello, M. G. Masucci

This study identifies BPLF1 as a regulator of TOP2 activity during EBV replication by modulating ubiquitination, SUMOylation, and DNA-damage response.

bioRxiv · Feb 26, 2021Microbiology

Type-I interferon signatures in SARS-CoV-2 infected Huh7 cells

X. Chen, E. Saccon, K. S. Appelberg, F. Mikaeloff, J. E. Rodriguez, B. S. Vinhas, T. Frisan, A. Vegvari, A. Mirazimi, U. Neogi, S. Gupta

This study identifies delayed and dysregulated type-I interferon signaling in SARS-CoV-2 infected Huh7 cells and shows that IFN-I pretreatment reduces susceptibility.

bioRxiv · Feb 4, 2021Microbiology

Tropism of SARS-CoV-2 in commonly used laboratory cell lines and their proteomic landscape during infection

E. Saccon, X. Chen, F. Mikaeloff, J. E. Rodriguez, L. Szekely, B. S. Vinhas, S. Krishnan, S. Byrareddy, T. Frisan, A. Vegvari, A. Mirazimi, U. Neogi, S. Gupta

This study assesses SARS-CoV-2 tropism and proteomic changes in human cell lines, finding cell-type-specific susceptibility and interferon signaling dysregulation.

bioRxiv · Aug 28, 2020Microbiology

Influence of the microenvironment on the modulation of the host response by the typhoid toxin

O. C. Martin, D. Butter, E. Paparouna, S. D. Theodorou, M. M. Haykal, E. Boutet-Robinet, T. Tebaldi, A. Bergonzini, M. Lopez Chiloeches, A. Wakeham, M. Rhen, T. Mak, V. Gorgoulis, I. S. Pateras, T. Frisan

This study investigates how typhoid toxin modulates host immune responses in health and disease by inducing DNA damage and senescence, with effects dependent on the host's inflammatory state.

bioRxiv · Jun 4, 2020Immunology