Author

L. C. Murphy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Research Focus:development & morphogenesis· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:differential expression· 1 Assay:electronic health records· 1

Frequent Co-Authors

P. Mill· 3 shared E. A. Hall· 2 shared L. McKie· 2 shared R. Megaw· 2 shared T. Quidwai· 2 shared A. Moye· 1 shared A. von Kriegsheim· 1 shared D. Kumar· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCell Biology

P. Mill

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Author profile →

3 papers

Recent·Most cited

Ciliary tip actin dynamics regulate the cadenceof photoreceptor disc formation

R. Megaw, A. Moye, Z. Zhang, F. Newton, F. McPhie, L. C. Murphy, L. McKie, F. He, M. K. Jungnickel, A. von Kriegsheim, L. Machesky, T. G. Wensel, P. Mill

This study shows that actin dynamics at photoreceptor cilia tips regulate disc formation, and RPGR mutations disrupt this process, leading to retinal degeneration.

bioRxiv · Nov 10, 2022Cell Biology

Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis.

E. A. Hall, D. Kumar, S. L. Prosser, P. L. Yeyati, V. Herranz-Pérez, J. M. Garcia Verdugo, L. Rose, L. McKie, D. O. Dodd, P. A. Tennant, R. Megaw, L. C. Murphy, M. Ferreira, G. Grimes, L. Williams, , P. Mill

This study shows that PCM1 and centriolar satellites are essential for efficient ciliogenesis by facilitating protein trafficking and remodeling of the mother centriole.

bioRxiv · Apr 4, 2022Cell Biology

A WDR35-dependent coatomer transports ciliary membrane proteins from the Golgi to the cilia

T. Quidwai, E. A. Hall, M. A. Keighren, W. Leng, P. Kiesel, J. N. Wells, L. C. Murphy, J. A. Marsh, G. Pigino, P. Mill

The paper shows WDR35 is part of a coatomer complex that transports ciliary membrane proteins from the Golgi to cilia, essential for cilia elongation.

bioRxiv · Dec 22, 2020 · PreprintCell Biology