A new variant of ASIC2 mediates sodium retention in nephrotic syndrome
M. Fila, A. Sassi, G. Brideau, L. Morla, P. Houillier, C. Walter, M. Gennaoui, L. Collignon, M. Keck, G. Planelles, N. Bakouh, M. Peuchmaur, G. Deschenes, I. Anegon, S. Remy, , A. Doucet
The paper identifies a truncated variant of ASIC2b responsible for sodium retention in idiopathic nephrotic syndrome, independent of ENaC and aldosterone.
bioRxiv · Feb 9, 2021Pathology