L. Di Michele

This paper introduces DNA-origami line-actants that control membrane domain organisation and fission in synthetic systems.

This paper demonstrates the creation of synthetic cells using DNA nanostructures that form compartmentalized architectures with targeted activities through phase separation and chemical modifications.

This study shows that C9orf72 hexanucleotide repeat expansions form RNA condensates via multimolecular G-quadruplexes, suggesting a therapeutic target for ALS/FTD.

This paper proposes a primitive cell cycle driven by thermal oscillations that enables genetic material reshuffling in prebiotic fatty acid vesicles, leading to the emergence of functional RNA-containing protocells.

This paper introduces a DNA-based platform that regulates cargo distribution between lipid domains using modular, dynamic DNA nanostructures.