Author

L. E. Kueffer

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Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. H. Andreotti· 1 shared D. Y.-w. Lin· 1 shared J. R. Engen· 1 shared P. Juneja· 1 shared T. E. Wales· 1 shared

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2023-2023 · peak 1/yr

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5 top collaborators · 10 mutual co-author links

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1 shared paperBiophysics

A. H. Andreotti

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1 paper

Recent·Most cited

BiophysicsbioRxivJun 2, 2023

Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states

D. Y.-w. Lin, L. E. Kueffer, P. Juneja…·A. H. Andreotti

This study presents the first structural analysis of full-length BTK, revealing conformational heterogeneity in the PHTH-PRR region and providing insights into BTK activation mechanisms.

DOI 10.7554/elife.89489

structural biologyexperimental assay

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