Control of human pancreatic beta cell kinome by GLP-1R biased agonism
J. Xiao, L. Eleid, T. Buenaventura, R. Boutry, A. Bonnefond, B. Jones, G. A. Rutter, P. Froguel, A. Tomas
This study compares kinase activity profiles in human pancreatic beta cells stimulated by GLP-1R agonists with different bias, revealing distinct kinomic responses and potential therapeutic targets.
bioRxiv · Feb 25, 2023Cell Biology