ImmunologybioRxivPreprint
ART duration and immunometabolic state determine efficacy of DC-based treatment restoring functional HIV- specific CD8+ T cells in PLWH.
M. Calvet-Mirabent, I. Sanchez-Cerrillo, N. Martin-Cofreces…·E. M.-G. Martin-Gayo
This study shows that ART duration affects CD8+ T cell function in HIV-1 patients, with longer ART improving DC-based immunotherapy outcomes through specific immunometabolic changes.
DOI 10.1101/2022.01.14.476403