BiochemistrybioRxiv
Meiotic chromosome synapsis depends on multivalent SYCE1-SIX6OS1 interactions that are disrupted in cases of human infertility
F. Sanchez-Saez, L. Gomez-H, O. M. Dunne…·O. R. Davies
This study identifies SYCE1-SIX6OS1 interactions critical for meiotic synapsis, showing that mutations disrupting these interactions cause human infertility.
DOI 10.1126/sciadv.abb1660