Author

L. Hoffner

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. Cho· 1 shared A. J. Crawford· 1 shared A. J. Ewald· 1 shared B. R. Si· 1 shared C. Jang· 1 shared C. Wong· 1 shared D. Wirtz· 1 shared G. C. Russo· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Cho

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1 paper

Recent·Most cited

Serine synthesis pathway upregulated by E-cadherin is essential for the proliferation and metastasis of breast cancers

G. Lee, C. Wong, A. Cho, J. J. West, A. J. Crawford, G. C. Russo, B. R. Si, J. Kim, L. Hoffner, C. Jang, M. Jung, R. D. Leone, K. Konstantopoulos, A. J. Ewald, D. Wirtz, S. Jeong

This study shows that E-cadherin upregulates the serine synthesis pathway in breast cancer cells, supporting proliferation and metastasis by providing metabolic precursors and resistance to oxidative stress.

bioRxiv · May 24, 2023 · PreprintCancer Biology