Microenvironmental sensing by fibroblasts controls macrophage population size
X. Zhou, R. A. Franklin, M. Adler…·R. Medzhitov
This study shows fibroblasts sense space and regulate macrophage numbers via growth factor production.
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3 papers
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X. Zhou, R. A. Franklin, M. Adler…·R. Medzhitov
This study shows fibroblasts sense space and regulate macrophage numbers via growth factor production.
E. Bjanes, R. G. Sillas, R. Matsuda…·I. E. Brodsky
This study shows that genetic targeting of Card19 disrupts Ninj1 expression, impairs macrophage cell lysis, and increases susceptibility to Yersinia infection.
B. A. Goods, M. H. Askenase, E. Markarian…·L. H. Sansing
The paper uses single-cell RNA-sequencing to study leukocyte dynamics in a living patient after intracerebral hemorrhage, revealing rapid immune responses and adaptations to the hematoma microenvironment.