BiophysicsbioRxivPreprint
The conformational landscape of a serpin N-terminal subdomain facilitates folding and in-cell quality control
U. Kaur, K. C. Kihn, H. Ke…·A. Gershenson
This paper investigates how the N-terminal subdomain of serpin 1-antitrypsin (AAT) influences folding and in-cell quality control by maintaining a dynamic conformational landscape.
DOI 10.1101/2023.04.24.537978