Cell BiologybioRxiv
HIF-1α induces glycolytic reprogramming in tissue-resident alveolar macrophagesto promote survival during acute lung injury
P. S. Woods, L. M. Kimmig, K. A. Sun…·G. M. Mutlu
This study shows hypoxia stabilizes HIF-1α in alveolar macrophages, promoting glycolytic reprogramming that enhances survival during acute lung injury.
DOI 10.7554/elife.77457