BiochemistrybioRxivPreprint
Design, Synthesis and Evaluation of Inhibitors of the SARS-CoV-2 nsp3 Macrodomain
L. M. Sherrill, E. E. Joya, A. Walker…·D. V. Ferraris
This study designs and synthesizes inhibitors targeting the SARS-CoV-2 nsp3 macrodomain, identifying compound 15c as a low-micromolar inhibitor with structural and thermal evidence of binding.
DOI 10.1101/2022.02.27.482176