Author

L. Marnin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 6 Approach:experimental assay· 5 Research Focus:cell type annotation· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

L. R. Butler· 5 shared N. Singh· 5 shared A. Rolandelli· 4 shared S. Samaddar· 4 shared A. J. O'Neal· 3 shared F. Cabrera Paz· 3 shared L. Valencia· 3 shared M. T. Mendes· 3 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersMicrobiology

L. R. Butler

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Tick extracellular vesicles alter keratinocyte function in the skin epidermis

L. Marnin, L. Valencia, H. Bogale, H. Laukaitis-Yousey, A. Rolandelli, C. R. Ferraz, A. J. O'Neal, A. Schmitter-Sanchez, E. Bencosme Cuevas, T.-T. Nguyen, B. Leal-Galvan, D. M. Rickert, M. T. Mendes, S. Samaddar, L. R. Butler, , J. H. F. Pedra

This study shows that tick extracellular vesicles alter keratinocyte function in the epidermis by inhibiting proliferation and wound closure, linked to phosphoinositide 3-kinase, KGF-1, and TGF-β.

bioRxiv · Nov 10, 2023 · PreprintMicrobiology

Rab27 in tick extracellular vesicle biogenesis and infection

L. R. Butler, N. Singh, L. Marnin, L. Valencia, A. O'Neal, F. Cabrera Paz, D. K. Shaw, A. Oliva Chavez, J. Pedra

This study identifies Rab27 as essential for tick extracellular vesicle biogenesis and its role in bacterial acquisition during feeding.

bioRxiv · Nov 2, 2023 · PreprintMicrobiology

Tick hemocytes have pleiotropic roles in microbial infection and arthropod fitness

A. Rolandelli, H. Laukaitis-Yousey, H. Bogale, N. Singh, S. Samaddar, A. ONeal, C. Ferraz, M. Butnaru, E. Mameli, B. Xia, M. T. Mendes, L. R. Butler, L. Marnin, F. Cabrera Paz, L. Valencia, , J. Pedra

This study identifies hemocyte heterogeneity and pleiotropic roles in ticks using multi-omics approaches, revealing their impact on immunity, metabolism, and arthropod fitness.

bioRxiv · Aug 31, 2023 · PreprintImmunology

Metabolic disruption impacts tick fitness and microbial relationships

S. Samaddar, A. J. O'Neal, L. Marnin, A. Rolandelli, N. Singh, X. Wang, L. R. Butler, P. Rangghran, H. J. Laukaitis, F. E. Cabrera Paz, G. M. Fiskum, B. M. Polster, J. H. Pedra

This study shows that metabolic changes in ticks affect their fitness and interactions with microbes, highlighting the role of BAIBA in these relationships.

bioRxiv · May 26, 2023Microbiology

CD36 homologs determine microbial resistance to the Lyme disease spirochete

A. J. O'Neal, N. Singh, I. S. Forrest, A. Rolandelli, X. Wang, D. K. Shaw, B. D. Young, S. Narasimhan, S. Dutta, G. A. Snyder, L. Marnin, L. R. Butler, S. Samaddar, M. T. Mendes, F. E. C. Paz, , J. H. F. Pedra

The paper identifies CD36 homologs as conserved lipid receptors mediating anti-Borrelia immunity in both ticks and humans.

bioRxiv · Feb 9, 2022 · PreprintImmunology

Immune factor of bacterial origin protects ticks against host microbial commensals

B. M. Hayes, A. D. Radkov, F. Yarza, S. Flores, J. R. Kim, Z. Zhao, K. W. Lexa, L. Marnin, J. Biboy, V. Bowcutt, W. Vollmer, J. H. Pedra, S. Chou

This study shows that a bacterial-derived immune factor in ticks protects them from host skin microbes but not from Lyme disease bacteria, revealing a complex interplay between ticks, their microbes, and hosts.

bioRxiv · Apr 10, 2020Evolutionary Biology