Author

L. Ostrer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Berger· 1 shared A. D. Baughn· 1 shared A. Khodursky· 1 shared A.-L. Kiffe-Delf· 1 shared B. Burckhardt· 1 shared B. Lungerich· 1 shared D. Podlesainski· 1 shared F. Kaschani· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Berger

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

α-Aminooxyacetic acid derivatives acting as pro-drugs against Mycobacterium tuberculosis

K. Vill, L. van Geelen, O. Michel, A.-L. Kiffe-Delf, A. Berger, D. Podlesainski, K. Stenzel, F. Kovacic, B. Lungerich, B. Burckhardt, T. A. :Crooks, M. D. Howe, L. Ostrer, Z. Jia, T. R. Ioerger, , R. Kalscheuer

This study identifies novel anti-TB pro-drugs based on α-aminooxyacetic acid that are effective against M. tuberculosis and show low cytotoxicity.

bioRxiv · Apr 4, 2024 · PreprintMicrobiology

Identification and characterization of pleiotropic high-persistence mutations in the beta subunit of the bacterial RNA polymerase

L. Ostrer, Y. Ji, A. Khodursky

This study identifies rpoB mutations that increase bacterial persistence by altering transcriptional programs and highlights their clinical relevance in antibiotic-resistant pathogens.

bioRxiv · Aug 19, 2020Microbiology