Author

L. Overbergh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

A. Perdigoto· 1 shared C. Gysemans· 1 shared C. J. Greenbaum· 1 shared C. Mathieu· 1 shared C. Speake· 1 shared D. Fignani· 1 shared D. L. Eizirik· 1 shared E. A. James· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperImmunology

A. Perdigoto

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Citrullination of glucokinase linked to autoimmune diabetes

M.-L. Yang, S. Horstman, R. Gee, P. Guyer, T. Lam, J. Kanyo, A. Perdigoto, C. Speake, C. J. Greenbaum, L. Overbergh, R. Kibbey, K. C. Herold, E. A. James, M. J. Mamula

This study identifies citrullination of glucokinase as an inflammatory-driven PTM that triggers autoimmunity and impairs glucose metabolism in Type 1 diabetes.

bioRxiv · Apr 28, 2021Immunology

SARS-CoV-2 receptor Angiotensin I-Converting Enzyme type 2 (ACE2) is expressed in human pancreatic β-cells and in the human pancreas microvasculature

D. Fignani, G. Licata, N. Brusco, L. Nigi, G. E. Grieco, L. Marselli, L. Overbergh, C. Gysemans, M. L. Colli, P. Marchetti, C. Mathieu, D. L. Eizirik, G. Sebastiani, F. Dotta

This study shows ACE2 is expressed in human pancreatic β-cells and microvasculature, suggesting a potential link between SARS-CoV-2 and diabetes through β-cell infection or microvasculature involvement.

bioRxiv · Jul 23, 2020Cell Biology