Author

J. Kanyo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Immunology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:cell signaling & trafficking· 4 Organism:human· 4 Assay:proteomics· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:metabolism & bioenergetics· 2

Frequent Co-Authors

T. Lam· 4 shared C. Speake· 2 shared E. A. James· 2 shared K. C. Herold· 2 shared M.-L. Yang· 2 shared R. Gee· 2 shared A. B. Mehrtash· 1 shared A. Datye· 1 shared

Activity by Year

2021-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersCell Biology

T. Lam

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Dual regulation of SLC25A39 by AFG3L2 and iron controls mitochondrial glutathione homeostasis

X. Shi, M. DeCiucis, K. A. Grabinska, J. Kanyo, A. Liu, T. Lam, H. Shen

The paper identifies dual regulation of SLC25A39 by AFG3L2 and iron, showing how this controls mitochondrial glutathione homeostasis in neurons.

bioRxiv · Nov 6, 2023Cell Biology

Mechanosensing through talin 1 contributes to tissue mechanical homeostasis

M. V. Chanduri, A. Kumar, D. Weiss, N. Emuna, I. Barsukov, M. Shi, K. Tanaka, X. Wang, A. Datye, J. Kanyo, F. Collin, T. Lam, U. D. Schwarz, S. Bai, T. Nottoli, , M. A. Schwartz

This study shows that mutations in talin1 alter cellular stiffness sensing, leading to changes in ECM mechanical properties and aortic compliance.

bioRxiv · Sep 3, 2023 · PreprintCell Biology

A versatile new ubiquitin detection and purification tool derived from a bacterial deubiquitylase

M. Zhang, J. M. Berk, A. B. Mehrtash, J. Kanyo, M. Hochstrasser

The paper introduces OtUBD, a bacterial deubiquitylase-derived domain for ubiquitin detection and purification, showing its effectiveness in isolating ubiquitylated proteins from yeast and human samples.

bioRxiv · Dec 2, 2021 · PreprintBiochemistry

Carbonyl Post-Translational Modification Associated with Early Onset Type 1 Diabetes Autoimmunity

M.-L. Yang, S. Connolly, R. Gee, T. Lam, J. Kanyo, S. G. Clarke, C. F. Clarke, E. A. James, C. Speake, C. Evans-Molina, L. Wen, K. C. Herold, M. Mamula

The paper identifies carbonylated P4Hb as an autoantigen in type 1 diabetes, detected before hyperglycemia in NOD mice and early human disease.

bioRxiv · Jun 15, 2021 · PreprintImmunology

Citrullination of glucokinase linked to autoimmune diabetes

M.-L. Yang, S. Horstman, R. Gee, P. Guyer, T. Lam, J. Kanyo, A. Perdigoto, C. Speake, C. J. Greenbaum, L. Overbergh, R. Kibbey, K. C. Herold, E. A. James, M. J. Mamula

This study identifies citrullination of glucokinase as an inflammatory-driven PTM that triggers autoimmunity and impairs glucose metabolism in Type 1 diabetes.

bioRxiv · Apr 28, 2021Immunology