Author

L. Pathak

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

B. Das· 4 shared B. Pal· 4 shared P. J. Saikia· 3 shared S. Bhuyan· 3 shared S. Gayan· 3 shared D. Baishya· 2 shared J. Talukdar· 2 shared R. Das· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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4 shared papersCancer Biology

B. Das

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Fusobacterium nucleatum present in the saliva of oral cancer subjects can activate niche defense of oral squamous cell carcinoma

P. J. Saikia, L. Pathak, S. Mitra, I. S. Akeel, B. Pal, T. Baishya, R. Das, B. Das

The paper investigates how Fusobacterium nucleatum in saliva activates a tumor stemness defense phenotype in oral cancer stem cells, contributing to cancer progression and relapse.

bioRxiv · Oct 10, 2023 · PreprintCancer Biology

Targeting tumor stemness switch phenotype by activating pathogen induced stem cell niche defense

B. Das, S. Bhuyan, B. Pal, L. Pathak, P. J. Saikia, S. Mitra, S. Gayan, R. B. Mokhtari, H. Li, C. V. Ramana, D. Baishya

The paper shows that tumor stemness switch phenotype CSCs undergo bystander apoptosis when infected with BCG or Mtb, activating a niche defense mechanism with anti-tumor and anti-microbial effects.

bioRxiv · Mar 25, 2022Cancer Biology

Stem cell basis of a host driven transmission of antigen packed aerosols: a novel mechanism of natural vaccination for tuberculosis

B. Das, L. Pathak, S. Gayan, B. Pal, P. j. Saikia, T. Baishya, N. R. Das, R. Das, M. Maral, R. Mahanta, S. Bhuyan, P. Gautam, J. Talukdar, S. Sandhya, D. Kalita, , I. Pulu

The paper investigates a novel natural vaccination mechanism where tuberculosis-infected individuals spread antigen-loaded extracellular vesicles via aerosols, inducing herd immunity in healthy mice.

bioRxiv · Nov 14, 2020 · PreprintImmunology

Coronavirus activates a stem cell-mediated defense mechanism that reactivates dormant tuberculosis: implications in COVID-19 pandemic

L. Pathak, S. Gayan, B. Pal, J. Talukdar, S. Bhuyan, S. Sandhya, H. Yeger, D. Baishya, B. Das

The paper shows that coronavirus infection in mice reduces viral loads by reactivating dormant tuberculosis through stem cell reprogramming, suggesting a potential defense mechanism with implications for COVID-19 vaccine development.

bioRxiv · May 6, 2020 · PreprintMicrobiology