Targeting tumor stemness switch phenotype by activating pathogen induced stem cell niche defense
B. Das, S. Bhuyan, B. Pal, L. Pathak, P. J. Saikia, S. Mitra, S. Gayan, R. B. Mokhtari, H. Li, C. V. Ramana, D. Baishya
The paper shows that tumor stemness switch phenotype CSCs undergo bystander apoptosis when infected with BCG or Mtb, activating a niche defense mechanism with anti-tumor and anti-microbial effects.
bioRxiv · Mar 25, 2022Cancer Biology