B. Das

(p)ppGpp and DksA play crucial role in reducing the efficacy of b-lactam antibiotics by modulating bacterial membrane permeability

This study shows that (p)ppGpp and DksA reduce the effectiveness of beta-lactam antibiotics by altering bacterial membrane permeability and peptidoglycan biosynthesis in Vibrio cholerae.

Elucidating the link between binding statistics and Shannon information in biological cooperative networks

The paper investigates the relationship between binding statistics and Shannon information in cooperative biological networks using two models.

Preclinical assessment of MAGMAS inhibitor as a potential therapy for pediatric medulloblastoma

This study evaluates the efficacy of the MAGMAS inhibitor BT9 in medulloblastoma cell lines and mice, showing in vitro antitumor effects but no survival benefit in vivo.

Non-canonical NF-κB signaling promotes intestinal inflammation by restraining the tolerogenic β-catenin-Raldh2 axis in dendritic cells

From the Wild to the City: How Domestication and Urbanization Reshape Animal Gut Microbiome

This review examines how domestication and urbanization alter gut microbiomes in animals, comparing their effects on microbial communities and ecological implications.

Fusobacterium nucleatum present in the saliva of oral cancer subjects can activate niche defense of oral squamous cell carcinoma

The paper investigates how Fusobacterium nucleatum in saliva activates a tumor stemness defense phenotype in oral cancer stem cells, contributing to cancer progression and relapse.

Differential expression of miRNAs between Young-Onset and Late-Onset Indian colorectal carcinoma patients

The paper identifies differentially expressed miRNAs between young-onset and late-onset colorectal carcinoma patients and links them to epithelial-mesenchymal transition and tumor progression.

A signalling rheostat controls chromosome segregation fidelity during early lineage specification and neurogenesis by modulating DNA replication stress

The paper identifies a signalling rheostat involving WNT, BMP, and FGF that modulates DNA replication stress and chromosome segregation fidelity during lineage specification and neurogenesis.

Uip4 governs growth phase-dependent organelle remodeling by modulating Saccharomyces cerevisiae lipidome

This study shows that Uip4 regulates organelle remodeling and lipid homeostasis in yeast during nutrient limitation by modulating lipidome profiles and organelle interactions.

Both behavior-manipulating and non-manipulating entomopathogenic fungi affect rhythmic gene expression in carpenter ant foragers upon infection

This study compares how two fungal infections, one behavior-manipulating and one non-manipulating, affect daily gene expression rhythms in carpenter ant foragers.

Ancestral SARS-CoV-2 driven antibody repertoire diversity in an unvaccinated individual correlates with expanded neutralization breadth

The paper examines antibody diversity in an unvaccinated SARS-CoV-2 infected individual, finding that post-vaccination neutralization breadth against Omicron variants is comparable to vaccinated individuals and breakthrough infections.

Targeting tumor stemness switch phenotype by activating pathogen induced stem cell niche defense

The paper shows that tumor stemness switch phenotype CSCs undergo bystander apoptosis when infected with BCG or Mtb, activating a niche defense mechanism with anti-tumor and anti-microbial effects.

Zn-dependent structural transition of SOD1 modulates its ability to undergo liquid-liquid phase separation.

This study shows that Zn-dependent structural changes in SOD1 affect its ability to undergo liquid-liquid phase separation, which may contribute to ALS pathology.

Chlorpyrifos degradation by combined solar photo-Fenton and bacterial metabolism and simultaneous toxicity analysis in zebrafish (Danio rerio)

This study evaluates the combined solar photo-Fenton and bacterial degradation of chlorpyrifos in wastewater and assesses its toxicity to zebrafish.

The Effect of a Fennel Extract on the STAT Signaling and Intestinal Barrier Function

This study shows that fennel extract improves intestinal barrier function and reduces STAT pathway activation in both in vitro and in vivo models of inflammation.

The metal cofactor zinc and interacting membranes modulate SOD1 conformation-aggregation landscape in an in vitro ALS Model

This study shows that Zn absence, not Cu, affects SOD1 membrane attachment and aggregation in an ALS model, linking it to disease progression.

Time-course RNASeq of Camponotus floridanus forager and nurse ant brains indicate links between plasticity in the biological clock and behavioral division of labor

The paper analyzes time-course RNASeq data from Camponotus floridanus forager and nurse ant brains to identify gene expression differences linked to behavioral division of labor and circadian rhythms.

Stem cell basis of a host driven transmission of antigen packed aerosols: a novel mechanism of natural vaccination for tuberculosis

The paper investigates a novel natural vaccination mechanism where tuberculosis-infected individuals spread antigen-loaded extracellular vesicles via aerosols, inducing herd immunity in healthy mice.

Aberrant Epithelial Differentiation Contributes to Pathogenesis in a Murine Model of Congenital Tufting Enteropathy

This study shows that loss of EpCAM in CTE mice leads to altered intestinal cell differentiation, increasing absorptive cells and decreasing secretory cells, which can be partially reversed by DAPT treatment.

Detection of 'relict' western lineage of citrus tristeza virus virulent genotype in declining Arunachal Wakro orange

The paper identifies a relict western lineage of citrus tristeza virus virulent genotype VT in declining Arunachal Wakro orange orchards, distinct from other Indian and neighboring CTV sequences.

Coronavirus activates a stem cell-mediated defense mechanism that reactivates dormant tuberculosis: implications in COVID-19 pandemic

The paper shows that coronavirus infection in mice reduces viral loads by reactivating dormant tuberculosis through stem cell reprogramming, suggesting a potential defense mechanism with implications for COVID-19 vaccine development.

Bioremediation of chlorpyrifos and 3,5,6-trichloro-2-pyridinol (TCP) by a paddy field bacterial isolate: Insights from genome analysis for possible biodegradation pathway

The paper isolates a bacterial strain capable of degrading chlorpyrifos and its metabolite TCP, identifies potential degradation genes, and highlights its bioremediation potential.

Draft genome sequence of a popular Indian tea genotype TV-1

The paper presents the first draft genome sequence of the Indian tea cultivar TV-1, providing insights into its genetic structure and potential for distinguishing it from other tea varieties.

Humidity as a non-pharmaceutical intervention for influenza A

This study shows that increasing classroom humidity reduces influenza virus presence and infectivity in preschool settings.