Author

B. Pal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Biochemistry· 2 Immunology· 2 Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Organism:human· 6 Research Focus:cell type annotation· 4 Research Focus:host-pathogen & immune response· 3 Approach:statistical model· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2

Frequent Co-Authors

B. Das· 4 shared L. Pathak· 4 shared P. J. Saikia· 3 shared S. Bhuyan· 3 shared S. Gayan· 3 shared S. Mangiola· 3 shared A. T. Papenfuss· 2 shared D. Baishya· 2 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersCancer Biology

B. Das

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Author profile →

10 papers

Recent·Most cited

The circulating immune cell landscape stratifies metastatic burden in breast cancer patients

S. Mangiola, R. Brown, J. Berthelet, S. Guleria, C. Liyanage, S. Ostrouska, J. Wilcox, M. Merdas, P. F. Larsen, C. Bell, J. Schroder, L. Mielke, J. Mariadason, S. Chang-Hao Tsao, Y. Chen, , B. Pal

This study identifies immune cell signatures in peripheral blood that correlate with metastatic burden in breast cancer patients using single-cell transcriptomics.

bioRxiv · Nov 1, 2023 · PreprintCancer Biology

Fusobacterium nucleatum present in the saliva of oral cancer subjects can activate niche defense of oral squamous cell carcinoma

P. J. Saikia, L. Pathak, S. Mitra, I. S. Akeel, B. Pal, T. Baishya, R. Das, B. Das

The paper investigates how Fusobacterium nucleatum in saliva activates a tumor stemness defense phenotype in oral cancer stem cells, contributing to cancer progression and relapse.

bioRxiv · Oct 10, 2023 · PreprintCancer Biology

Development and Analytical Evaluation of a Point-of-Care Electrochemical Biosensor for Rapid and Accurate SARS-CoV-2 Detection

M. Meshesha, A. Sardar, R. Supekar, L. Bhattacharjee, S. Chatterjee, N. Halder, K. Mohanta, B. Pal

This paper develops an electrochemical biosensor for rapid and accurate SARS-CoV-2 detection with high sensitivity and specificity.

bioRxiv · Aug 8, 2023 · PreprintBioengineering

A multi-organ map of the human immune system across age, sex and ethnicity

S. Mangiola, M. Milton, N. Ranathunga, C. LiWaiSuen, A. Odainic, E. Yang, W. Hutchison, A. Garnham, J. Iskander, B. Pal, V. J. Yadav, F. Rossello, V. Carey, A. Kallies, S. Bedoui, , A. T. Papenfuss

The paper creates a comprehensive immune system map across age, sex, and ethnicity using single-cell RNA sequencing data, revealing immune ageing patterns and ethnic diversity in immune checkpoints.

bioRxiv · Jun 8, 2023 · PreprintImmunology

Targeting tumor stemness switch phenotype by activating pathogen induced stem cell niche defense

B. Das, S. Bhuyan, B. Pal, L. Pathak, P. J. Saikia, S. Mitra, S. Gayan, R. B. Mokhtari, H. Li, C. V. Ramana, D. Baishya

The paper shows that tumor stemness switch phenotype CSCs undergo bystander apoptosis when infected with BCG or Mtb, activating a niche defense mechanism with anti-tumor and anti-microbial effects.

bioRxiv · Mar 25, 2022Cancer Biology

DIP2 is a unique regulator of diacylglycerol lipid homeostasis in eukaryotes

S. Mondal, P. Kinatukara, S. Singh, S. Shambhavi, G. S. Patil, N. Dubey, S. H. Singh, B. Pal, P. C. Shekar, S. S. Kamat, R. Sankaranarayanan

This study identifies DIP2 as a regulator of specific diacylglycerol (DAG) subsets in yeast, fly, and mouse, showing its role in preventing toxic DAG accumulation and modulating lipid homeostasis.

bioRxiv · Feb 7, 2022Biochemistry

A universal pocket in FAALs ensures redirection of fatty acid pool away from CoA-based activation

G. S. Patil, P. Kinatukara, S. Mondal, S. Shambhavi, K. D. Patel, S. Pramanik, N. Dubey, S. Narasimhan, M. K. Madduri, B. Pal, R. S. Gokhale, R. Sankaranarayanan

The paper identifies a unique binding pocket in FAALs that allows them to selectively use holo-ACP over CoA, enabling CoA-independent fatty acid activation and lipid biosynthesis.

bioRxiv · May 4, 2021Biochemistry

Stem cell basis of a host driven transmission of antigen packed aerosols: a novel mechanism of natural vaccination for tuberculosis

B. Das, L. Pathak, S. Gayan, B. Pal, P. j. Saikia, T. Baishya, N. R. Das, R. Das, M. Maral, R. Mahanta, S. Bhuyan, P. Gautam, J. Talukdar, S. Sandhya, D. Kalita, , I. Pulu

The paper investigates a novel natural vaccination mechanism where tuberculosis-infected individuals spread antigen-loaded extracellular vesicles via aerosols, inducing herd immunity in healthy mice.

bioRxiv · Nov 14, 2020 · PreprintImmunology

Coronavirus activates a stem cell-mediated defense mechanism that reactivates dormant tuberculosis: implications in COVID-19 pandemic

L. Pathak, S. Gayan, B. Pal, J. Talukdar, S. Bhuyan, S. Sandhya, H. Yeger, D. Baishya, B. Das

The paper shows that coronavirus infection in mice reduces viral loads by reactivating dormant tuberculosis through stem cell reprogramming, suggesting a potential defense mechanism with implications for COVID-19 vaccine development.

bioRxiv · May 6, 2020 · PreprintMicrobiology

Transcriptome sequencing and multi-plex imaging of prostate cancer microenvironment reveals a dominant role for monocytic cells in progression

S. Mangiola, P. McCoy, M. Modrak, F. S. F. Guimaraes, D. Blashki, R. Stuchbery, S. P. Keam, M. Kerger, K. Chow, C. Nasa, M. Le Page, N. Lister, S. Monard, J. Peters, P. Dundee, , C. M. Hovens

This study uses transcriptome sequencing and multiplex imaging to show that monocytic cells drive prostate cancer progression and immune modulation.

bioRxiv · Mar 16, 2020 · PreprintCancer Biology