ImmunologybioRxiv
DJ-1 (Park7) affects the gut microbiome, metabolites, and development of Innate Lymphoid Cells (ILCs)
Y. Singh, C. Trautwein, A. Dhariwal…·O. Riess
This study shows that DJ-1 deficiency in mice alters gut microbiome composition, increases inflammatory markers, and reduces innate lymphoid cells, potentially contributing to Parkinson's disease pathogenesis.
DOI 10.1038/s41598-020-72903-w