ImmunologybioRxiv
The concerted action of E2-2 and HEB is critical for early lymphoid specification
T. Bouderlique, L. Pena Perez, S. Kharazi…·R. Mansson
This study shows that E2-2 and HEB are essential for early lymphoid specification, as their disruption blocks B-cell and T-cell development while leaving other hematopoietic lineages unaffected.
DOI 10.3389/fimmu.2019.00455