MicrobiologybioRxiv
Treatment history shapes the evolution of complex carbapenem-resistant phenotypes in Klebsiella spp.
T. Lithgow, T. Zhou, M. MCDONALD…·Q. Bao
This study shows that treatment history influences the evolution of carbapenem resistance in Klebsiella by shaping the genetic loci involved and their fitness costs.
DOI 10.7554/elife.83107