Author

L. Plappert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:organoid / primary culture· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. Prasse· 2 shared D. Jonigk· 2 shared A. Schambach· 1 shared B. Jaeger· 1 shared D. Klatt· 1 shared G. Kayser· 1 shared H. Kempf· 1 shared I. Nazarenko· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCell Biology

A. Prasse

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2 papers

Recent·Most cited

The use of cultured human alveolar basal cells to mimic honeycomb formation in idiopathic pulmonary fibrosis

S. Blumer, P. Khan, N. Artysh, L. Plappert, S. Savic, L. Knudsen, D. Jonigk, M. P. Kuehnel, A. Prasse, K. E. Hostettler

The paper uses cultured human alveolar basal cells to create in vitro and in vivo models that mimic honeycomb cyst formation in idiopathic pulmonary fibrosis.

bioRxiv · Sep 19, 2023Cell Biology

Airway Basal Cells show a dedifferentiated KRT17high Phenotype and promote Fibrosis in Idiopathic Pulmonary Fibrosis

B. Jaeger, J. C. Schupp, L. Plappert, O. Terwolbeck, G. Kayser, P. Engelhard, T. S. Adams, R. Zweigerdt, H. Kempf, S. Lienenklaus, W. Garrels, I. Nazarenko, D. Jonigk, M. Wygrecka, D. Klatt, , A. Prasse

This study identifies IPF-ABC as dedifferentiated KRT17high cells that promote fibrosis and shows SRC inhibition can reverse their profibrotic effects.

bioRxiv · Sep 4, 2020Cell Biology