Author

M. Wygrecka

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Research Focus:differential expression· 4 Organism:human· 4 Approach:experimental assay· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

G. Kwapiszewska· 3 shared B. M. Nagy· 2 shared F. Valzano· 2 shared G. Barreto· 2 shared L. M. Marsh· 2 shared N. Bordag· 2 shared V. Biasin· 2 shared A. Birnhuber· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersCell Biology

G. Kwapiszewska

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Adventitial fibroblasts direct smooth muscle cell-state transition in pulmonary vascular disease

S. Crnkovic, H. Thekkekara Puthenparampil, S. Mulch, V. Biasin, N. Radic, J. Wilhelm, M. Bartkuhn, E. Bonyadi Rad, A. Wawrzen, I. Matzer, A. Mitra, R. D. Leib, B. M. Nagy, A. Sahu-Osen, F. Valzano, , G. Kwapiszewska

The paper identifies disease-associated states in PASMC and PAAF from IPAH patients and identifies potential modulators of PASMC phenotypic transition.

bioRxiv · May 15, 2024Cell Biology

Extracellular vesicles induce aggressive lung cancervia non-canonical integrin-EGFR-KRAS signaling

K. Rubio, A. Romero, P. Sarvari, S. Guenther, A. Mehta, B. Bassaly, P. Braubach, G. Dobreva, M. Wygrecka, S. Gattenloehner, T. Braun, A. Tresch, J. Graumann, G. Barreto

This study identifies a non-canonical ITGB2 signaling pathway that activates EGFR and RAS/MAPK/ERK in SCLC, leading to aggressive tumor behavior and resistance to EGFR inhibitors.

bioRxiv · Aug 16, 2022Cancer Biology

Altered fibrin clot structure contributes to thrombosis risk in severe COVID-19

M. Wygrecka, A. Birnhuber, B. Seeliger, L. Michalick, O. Pak, A.-S. Schultz, F. Schramm, M. Zacharias, G. Gorkiewicz, S. David, T. Welte, J. J. Schmidt, N. Weissmann, R. T. Schermuly, G. Barreto, , K. T. Preissner

The paper shows that altered fibrin clot structure in severe COVID-19 patients contributes to thrombosis risk by forming compact, fibrinolysis-resistant clots.

bioRxiv · Sep 17, 2021Biochemistry

Airway Basal Cells show a dedifferentiated KRT17high Phenotype and promote Fibrosis in Idiopathic Pulmonary Fibrosis

B. Jaeger, J. C. Schupp, L. Plappert, O. Terwolbeck, G. Kayser, P. Engelhard, T. S. Adams, R. Zweigerdt, H. Kempf, S. Lienenklaus, W. Garrels, I. Nazarenko, D. Jonigk, M. Wygrecka, D. Klatt, , A. Prasse

This study identifies IPF-ABC as dedifferentiated KRT17high cells that promote fibrosis and shows SRC inhibition can reverse their profibrotic effects.

bioRxiv · Sep 4, 2020Cell Biology

Machine learning analysis of the bleomycin-mouse model reveals the compartmental and temporal inflammatory pulmonary fingerprint

N. Bordag, V. Biasin, D. Schnoegl, F. Valzano, K. Jandl, B. M. Nagy, N. Sharma, M. Wygrecka, G. Kwapiszewska, L. M. Marsh

The paper uses machine learning to analyze bleomycin-induced lung inflammation in mice, revealing temporal and compartmental changes in immune cell dynamics.

bioRxiv · May 22, 2020Immunology