Author

A. Prasse

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

B. Seeliger· 2 shared D. Jonigk· 2 shared L. Plappert· 2 shared N. Kaminski· 2 shared T. S. Adams· 2 shared A. Biswas· 1 shared A. Foti· 1 shared A. Schambach· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersImmunology

B. Seeliger

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Tyrosine halogenation converts α-defensins into potent immunomodulators

A. Foti, R. Hurwitz, K. Textoris-Taube, M. Muelleder, A. Biswas, P. Fahjen, M. Winkler, U. Abu Abed, D. Humme, S. Thee, A. Prasse, B. Seeliger, M. Ralser, A. Zychlinsky

The paper identifies that tyrosine halogenation of α-defensins by hypohalous acids converts them into immunomodulatory mediators, revealing a novel oxidative mechanism in neutrophil function.

bioRxiv · Nov 1, 2023 · PreprintImmunology

The use of cultured human alveolar basal cells to mimic honeycomb formation in idiopathic pulmonary fibrosis

S. Blumer, P. Khan, N. Artysh, L. Plappert, S. Savic, L. Knudsen, D. Jonigk, M. P. Kuehnel, A. Prasse, K. E. Hostettler

The paper uses cultured human alveolar basal cells to create in vitro and in vivo models that mimic honeycomb cyst formation in idiopathic pulmonary fibrosis.

bioRxiv · Sep 19, 2023Cell Biology

High CXCL6 drives matrix expression and correlate with markers of poor outcome in IPF

H. Bahudhanapati, J. Tan, R.-M. Apel, B. Seeliger, X. Li, T.-Y. Chen, D. Sullivan, J. Sembrat, M. Rojas, E. Valenzi, R. A. Lafyatis, C. Jawale, P. Biswas, J. Tedrow, T. S. Adams, , D. J. Kass

This study identifies CXCL6 as a pro-fibrotic factor in IPF, showing it reduces cAMP, increases collagen and -SMA, and correlates with poor patient survival.

bioRxiv · Jun 22, 2021 · PreprintCell Biology

Airway Basal Cells show a dedifferentiated KRT17high Phenotype and promote Fibrosis in Idiopathic Pulmonary Fibrosis

B. Jaeger, J. C. Schupp, L. Plappert, O. Terwolbeck, G. Kayser, P. Engelhard, T. S. Adams, R. Zweigerdt, H. Kempf, S. Lienenklaus, W. Garrels, I. Nazarenko, D. Jonigk, M. Wygrecka, D. Klatt, , A. Prasse

This study identifies IPF-ABC as dedifferentiated KRT17high cells that promote fibrosis and shows SRC inhibition can reverse their profibrotic effects.

bioRxiv · Sep 4, 2020Cell Biology