P. Khan

The use of cultured human alveolar basal cells to mimic honeycomb formation in idiopathic pulmonary fibrosis

The paper uses cultured human alveolar basal cells to create in vitro and in vivo models that mimic honeycomb cyst formation in idiopathic pulmonary fibrosis.

Repressing ABCB7 Potentiates Cisplatin Response in Pediatric Group 3 Medulloblastoma by Triggering Ferroptosis

This study shows that repressing ABCB7 in group 3 medulloblastoma triggers ferroptosis, enhancing cisplatin response and survival.

Glutathione regulates transcriptional activation of iron transporters via S-nitrosylation of bHLH factors to modulate subcellular iron homeostasis

This study shows glutathione regulates subcellular iron homeostasis under iron deficiency by activating iron transporters through S-nitrosylation of bHLH transcription factors.

In vitro culture of aberrant basal-like cells from fibrotic lung tissue

The paper cultures and characterizes aberrant basal-like cells from fibrotic lung tissue, finding they co-express epithelial and mesenchymal markers and show disease-specific transcriptomic differences between IPF and other ILD patients.

Assessment of NR4A Ligands that Directly Bind and Modulate the Orphan Nuclear Receptor Nurr1

The paper assesses twelve NR4A ligands to determine if they directly bind and modulate Nurr1 or act through effector proteins, finding some bind directly while others do not.