R. Zweigerdt

This study transplants human iPSC-derived cardiomyocyte aggregates into non-human primates with myocardial infarction, showing efficient engraftment and functional recovery with lower cell doses than previous single-cell approaches.

This paper shows that targeted therapies for BCR-ABL+ ALL can cause heart damage, but some treatments like dasatinib and venetoclax can reverse cardiac defects while others cannot.

This paper develops a method to produce vascularised liver organoids from human PSCs without 2D patterning or ECM, demonstrating liver-like functions and cellular complexity.

This study identifies IPF-ABC as dedifferentiated KRT17high cells that promote fibrosis and shows SRC inhibition can reverse their profibrotic effects.