Author

L. Renou

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Organism:human· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

F. Pflumio· 3 shared J. Calvo· 3 shared A. Petit· 2 shared B. Uzan· 2 shared P. Ballerini· 2 shared V. Barroca· 2 shared A. Kypraios· 1 shared A. Magnani· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCancer Biology

F. Pflumio

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

T-cell acute lymphoblastic leukemia progression is supported by inflammatory molecules including Hepatocyte Growth factor

C. Le Maout, L. Fahy, L. Renou, C. Devanand, C. Duwat, V. Barroca, M. Le Gall, P. Ballerini, A. Petit, J. Calvo, B. Uzan, F. Pflumio, V. Petit

This study identifies an inflammatory microenvironment in T-ALL that supports progression, with HGF as a potential therapeutic target.

bioRxiv · Apr 24, 2024Cancer Biology

Humanized in vivo bone marrow models orchestrate multi-lineage human hematopoietic cell development

L. Renou, W. SUN, C. Friedrich, K. Galant, C. Conrad, E. Plantier, K. Schallmoser, L. Kritsch, V. Barroca, S. Devanand, N. Dechamps, A. Reinisch, J. Martinovic, A. Magnani, L. Faivre, , F. Pflumio

This study characterizes a humanized in vivo bone marrow model, hOss, showing its impact on human hematopoietic development and clonal interactions.

bioRxiv · Apr 8, 2024 · PreprintCell Biology

High CD44 expression identifies rare chemoresistant leukemic cells endowed with enhanced E-Selectin binding in T-ALL

J. Calvo, I. Naguibneva, A. Kypraios, B. Uzan, B. Gaillard, L. Bellenger, L. Renou, C. Antoniewski, H. Lapillone, A. Petit, P. Ballerini, S. J. Mancini, T. Marchand, J.-F. Peyron, F. Pflumio

The paper identifies a chemoresistant leukemic stem cell population in T-ALL with high CD44 expression and enhanced E-selectin binding, associated with poor prognosis and relapse.

bioRxiv · Dec 20, 2023 · PreprintCancer Biology