Author

L. S. Pakkiri

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

C. L. Drum· 2 shared A. A. Widjaja· 1 shared A. F. Vallejo· 1 shared A. Hearn· 1 shared B. K. Singh· 1 shared B. NG· 1 shared B. Vilaysane· 1 shared C. Bai· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPathology

C. L. Drum

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Author profile →

2 papers

Recent·Most cited

PathologybioRxivPreprintOct 5, 2023

MMPs and NETs are detrimental in human CNS-tuberculosis and MMP inhibition in a mouse model improves survival

X. Y. Poh, F. K. Loh, C. Bai…·C. W. M. Ong

The paper identifies elevated MMPs and NETs in CNS-TB patients and shows MMP inhibition improves survival in a mouse model.

DOI 10.1101/2023.10.05.561002

𝕏 PostBluesky

PhysiologybioRxivNov 4, 2019

Redefining Interleukin 11 as a regeneration-limiting hepatotoxin

A. A. Widjaja, J. R. Dong, E. Adami…·S. A. Cook

This study reveals IL11 as a hepatotoxin that limits liver regeneration after APAP overdose, showing its inhibition of endogenous IL11 activity protects mice.

DOI 10.1126/scitranslmed.aba8146

mouseexperimental assay

𝕏 PostBluesky